The GT Aerospace Systems Design Laboratory stands at the forefront of systems design, architecture, and optimization, holding the distinction of being the largest lab of its kind globally. Renowned for its contributions to graduate education and research in systems engineering and vehicle design, the lab is dedicated to cultivating the next generation of highly skilled engineers for academia, industry, and government. Leveraging cutting-edge multi-disciplinary, physics-based methodologies, the lab pioneers innovative approaches to design complex systems and systems of systems. Additionally, it offers independent and credible assessment capabilities, employing integrated, quantifiable methodologies to serve both government and industry. Recent research endeavors have focused on merging ASDL's signature methods with advancements in computing to enable large-scale virtual experimentation for complex systems design, pushing the boundaries of innovation in aerospace engineering.