The Net Zero Freight Systems Program is developing the solution pathways for a resilient freight system with zero greenhouse gas emissions, lower environmental impacts, and greater societal benefit than today’s system. The initiative will: reduce freight system emissions by simultaneously addressing fuels, vehicles, and the design of effective material movement systems and combine teaching and research with industrial, government, and civil society engagement to identify and amplify priority improvement opportunities. We provide vision, pathways, options, and analysis to decision makers and the public, and we track progress over time.